Discussion for Patient: Female Only The Female Only Group is usually a reflection of sugar handling difficulties compounded by liver-gallbladder dysfunction that classically affects adrenal function. High stress and the over-consumption of sugar and refined carbohydrates have led to most of the symptoms in this group. This problem is very common in our society because of the misunderstanding of the importance of good fats in our diet, and the overuse of carbo-hydrates. Much of the solution is accomplished by addressing the causes like sugar, chocolate, soft drinks, alcohol and caffeine intake, lack of rest, and too much emotional upset. One of the best supports for most of the symptoms in this group is Dr. Page's Phase 1 & 2 Diet Plan which is low in refined carbohydrates, and high in quality carbohydrates. SP: Symplex F MH: Chaste Tree, Wild Yam Complex, Dong Quai Nutritional Comments If you are looking at a symptom survey of a 45-year-old female and the female-only symptoms are the most predominant, look to liver and sugar handling difficulties, then the adrenals before addressing the ovaries and/ or uterus directly. Classically, the female group symptoms get there through Groups 3 and 5, and multiple responses in Group 7 and Female Only (undermining process of the other endocrine organs). Much of the damage leading to female problems is due to pancreas endocrine/exocrine stress with sugar and refined carbohydrates, and the liver with poor quality lipid intake (fried foods, hydrogenated fats, etc.). The resultant adrenal stress and destabilization of the endocrine glands result in the typical symptoms of the Female Only Group. Much of the solution is accomplished by addressing the causes like sugar, chocolate, soft drinks, alcohol and caffeine intake, lack of rest, and too much emotional upset. One sure way to fail is to treat Female Only Group symptoms alone. Progesterone is produced by the corpus luteum under the influence of LH. Low progesterone may be the result of thyroid insufficiency (which may be secondary to adrenal, anterior pituitary, or estrogen stress). Progesterone opposes estrogen. Placental and mammary concentrates have progesterone activity. Progesterone decreases bleeding. Progesterone insufficiency is typically associated with a menstrual cycle shorter than 28 days, heavy menstrual bleeding, fluid retention during menses, premenstrual tension dominated by nervousness, headache, nausea, and fluid retention, menstrual bleeding longer than 3 days, menstrual cramps, uterine fibroids, breast lumps and breast swelling with increased subcutaneous fluid, decreased systolic blood pressure and pulse pressure, decreased pulse and temperature, poor retention of sodium and chloride, vomiting and toxemia of pregnancy, uterine contractions during early pregnancy, and habitual miscarriage. Progesterone excess can be due to incomplete breakdown by liver, sympathetic, or sugar metabolic imbalances. Symptoms include a menstrual cycle longer than 28 days, scanty menstrual flow, acne, greasy hair and skin, or breast tenderness during menses, premenstrual depression, increased temperature, dry vagina and/or thick discharge, and excess retention of sodium, chloride, phosphorus and sulfur. Estrogen is produced by the ovarian follicle under the influence of FSH. Estrogen insufficiency can be due to ovarian or pituitary insufficiency, and after menopause, adrenal insufficiency. Vitamin B6 reduces blood estrogen, and fiber binds estrogen in the gut preventing its reabsorption during enterohepatic re-circulation and thus may be reduced with fiber supplementation and vegetarian diets. Estrogen can also be lost in the feces if intestinal bacteria are destroyed since gut bacteria deconjugate estrogen for recirculation back into the body. Symptoms of estrogen insufficiency include increased diastolic blood pressure, a tendency to ulcers, sterility, pain, cramping, and tension during but not before menstruation, decreased menstrual blood flow, menstrual cycle longer than 28 days, a hypoplastic, weak uterus and senile vaginitis, menopausal hot flashes, anemia, poor retention of sodium, chloride, potassium and calcium, poor calcium assimilation, and excess retention of phosphorus. Estrogen decreases the cycle length and causes fat deposits in the breasts. Estrogen production is stimulated by vitamin E which also reduces the above breast symptoms. Estrogen excess can also occur with liver overload preventing estrogen breakdown, parasympathetic dominance, excess fat or insufficient fiber intake that increases enterohepatic circulation, excess coffee, tea, vitamin E and chocolate. Features of excessive estrogen include reduced diastolic blood pressure, premenstrual tension dominated by nervousness, head-aches, nausea, & fluid retention, uterine smooth muscle cramps/spasms due to increased extracellular potassium/decreased intra-cellular calcium, watery vaginal discharge, excess menstrual flow lasting only 2-3 days, decreased thyroid effect due to impedance of T4 conversion to T3 with reduced temperature, tendency to vein problems, tendency to schizophrenia, an increased incidence of breast, lung, liver, and GI cancer, gynic qualities, increased calcium and phosphorus retention.